Strategies for systems-level metabolic engineering.
The ten strategies of systems metabolic engineering have been featured in Nature Biotechnology released online in October , which is entitled "Systems strategies for developing industrial microbial strains. The strategies cover economic, state-of-the-art biological techniques and traditional bioprocess aspects. These ten strategies were articulated with successful examples of the production of L-arginine using Corynebacterium glutamicum , 1,4-butanediol using Escherichia coli , and L-lysine and bio-nylon using C.
Professor Sang Yup Lee said, "At the moment, the chance of commercializing microbial strains developed in academic labs is very low.
The strategies of systems metabolic engineering outlined in this analysis can serve as guidelines when developing industrial microbial strains. We hope that these strategies contribute to improving opportunities to commercialize microbial strains developed in academic labs with drastically reduced costs and efforts, and that a large fraction of petroleum-based processes will be replaced with sustainable bioprocesses.
Note: Content may be edited for style and length. Science News. Systems strategies for developing industrial microbial strains.
Nature Biotechnology , ; 33 10 : DOI: ScienceDaily, 12 October Establishment of systems metabolic engineering strategies to develop microbial strains. Retrieved September 23, from www. Coli Strains Jan.
Startseite Chemie, Biowissenschaften, Agrarwissenschaften Entwicklungsbiologie Mikrobiologie nichtmedizinisch. Erschienen: Auf die Merkliste Drucken Weiterempfehlung. Hardcover Springer.
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Produktbeschreibung This volume reviews the current metabolic engineering tools and technologies from a practical point of view, and guides researchers as they overcome challenges at various stages of organism and bioprocess development. Written by leading experts in the field from both academia and industry, key topics include synthetic biology, pathway engineering, metabolic flux manipulation, adaptive evolution, and fermentation process scale-up.
It is suitable for non-specialists, and is a valuable resource for anyone embarking on the exciting path to harnessing the metabolic potential of microorganisms. Kundeninformationen Combines theory and practice Addresses challenges along the entire workflow from project conception to commercialization Includes most recent advances in the field. Ihr Name:.